POSTDOCTORAL POSITIONS ON OUR NATIONAL INSTITUTE ON AGING FUNDED BIOLOGY OF AGING TRAINING GRANT MAY BE AVAILABLE
If you are interested, please contact us and let us know which mentors (chosen from the list of faculty members from the Biology of Aging Training Grant - see list at right) with whom you could imagine working with.
designated as security sensitive positions; U.S. Citizenship or Permanent Resident Required.
The University of Texas Health Science Center at San Antonio is an Equal Employment Opportunity/Affirmative Action Employer including protected veterans and persons with disabilities
Cell Metabolism, Diabetes, and Aging
Two postdoctoral positions are available at Barshop Aging Institute of University of Texas Health Science Center at San Antonio, a leading institute in aging research, to work in the areas of signal transduction, cell metabolism, obesity, diabetes, fatty liver disease, and aging. Our ongoing research focuses on the nutrient regulation of glucose/lipid metabolism and energy balance, as well as the identification of therapeutic mechanisms for fatty liver disease and insulin resistance in diabetes and aging-related metabolic disease (Li Y, et al. Cell Metabolism, 2011; Gastroenterology, 2014; Luo T, et al. Diabetes, 2016). We generate a variety of genetically-modified mouse models and human disease-related animal models including obesity, non-alcoholic fatty liver disease, and aging-related metabolic diseases. The ideal candidate are exceptionally motivated, creative, and committed to scientific discovery and have strong academic training in biochemistry, molecular and cell biology, and animal models. Candidates with a strong background in metabolism, ER stress or autophagy biology are strongly encouraged to apply for the positions. To apply, please submit a cover letter to Dr. Mengwei Zang’s email: Zang@uthscsa.edu and attach: curriculum vitae, a one-page personal statement describing your scientific accomplishments and research interests, and contact information (including phone numbers) of three references. For more information on the research work of Zang laboratory, please visit the following website: http://molecularmedicine.uthscsa.edu/FAC_Profile.aspx?facID=210
Mitochondrial dysfunction in aging-related metabolic diseases
A postdoctoral scholar position is available immediately at Barshop Aging Institute of University of Texas Health Science Center at San Antonio, a leading institute in aging research, to identify molecular mechanisms that links aging to the onset of aging-related metabolic diseases using molecular, cellular, metabolic, knockout mouse, and lipidomic approaches. The primary focus of the laboratory is on translational aspects of aging and aging-related diseases, including type 2 diabetes, obesity, diabetic complications, and cardiovascular diseases, with an overarching goal to develop novel treatments for these conditions. The laboratory pioneered the initiation identification and functional characterization of PERK kinase and several lipid metabolic enzymes, including the first cardiolipin remodeling enzyme which plays a key role in linking mitochondrial dysfunction to the onset of several aging-related diseases (Cell Metabolism, 12, 154-165; Proc Natl Acad Sci USA, 109(18):6975-80; Mol Cell Biol. 2013 Jul;33(13):2527-34). Required qualifications include a PhD degree in molecular biology, metabolic diseases, or mitochondrial biology with demonstrated productivity in biomedical research. Candidate must be fluent in English. Experience in working with mitochondrial biology and knockout mice are definitely a plus.
Qualified candidate should send a copy of resume and three names of references to Prof. Roger Shi at firstname.lastname@example.org. For more information of the research work of the laboratory, please visit http://www.barshop.uthscsa.edu/main/facultystaff/barshopfaculty/u226.
Dr. Ikeno's laboratory is studying the effects of oxidative stress on aging and age-related pathology, using unique animal models that overexpress or downregulate antioxidant enzymes, including thioredoxin and Cu/Zn SOD. Research projects include: (1) redox sensitive signaling with mice that overexpress thioredoxin 1 or 2; and (2) obesity/inflammation/oxidative damage/insulin signaling with Cu/ZnSOD transgenic rats or mice fed a high-fat diet; (3) anti-tumor actions of caloric restriction.
Experience in standard techniques of molecular and cellular biology is required. A strong research background in the area of oxidative stress and signaling is appreciated.
Please use the link provided to contact Dr. Ikeno for more information.