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The Barshop Institute for Longevity and Aging Studies

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Can metformin prevent frailty in prediabetic adults?
The National Institute on Aging awarded $2 million to UT Health San Antonio and its Sam & Ann Barshop Institute for Longevity & Aging Studies to find out.


“We are enrolling senior adults who are at least 65 and have prediabetes,” said Sara Espinoza, M.D., M.Sc., clinical investigator with the Sam & Ann Barshop Institute. “We seek older adults with prediabetes because they are at higher risk of becoming frail.”

The study is conducted at the South Texas Veterans Health Care System-Audie L. Murphy Hospital, a clinical partner of UT Health San Antonio. Study volunteers do not have to be veterans.

Prospective volunteers may call Barshop Clinical Research at (210) 450-0020.

Click Here to learn more about this Study




"DEPTOR Suppresses Lipogenesis and Ameliorates Hepatic Steatosis and Acute-on-Chronic Liver Injury in Alcoholic Liver Disease"


Published in Hepatology

Mengwei Zang, M.D., Ph.D., Associate Professor of Molecular Medicine




"mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1"

Published in Molecular Cell
Masahiro Morita, Ph.D., Assistant Professor of Molecular Medicine

The Barshop Institute is dedicated to the promotion of healthy aging for everyone. Its world-class scientific community of researchers and physicians seek discoveries to treat and ameliorate the underlying causes of aging, a cost-effective approach to broadly enhance the quality of later life. We invite you to explore our website to learn about the extraordinary work of our community of researchers and physicians.

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The Sam and Ann Barshop Institute for Longevity and Aging Studies

15355 Lambda Drive
San Antonio, Texas  78245
P: 210-562-6140 F: 210-562-6110

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UT Health San Antonio

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